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DewDiligence

07/20/20 11:45 AM

#233749 RE: Whalatane #233746

PFE/BNTX may have a slight edge versus MRNA at this point, but that’s far from clear-cut.

biocqr

07/20/20 1:01 PM

#233758 RE: Whalatane #233746

Re: MRNA vs Pfizer/BioNTech: Derek Lowe analyzes the Pfizer data with comparisons to Moderna's...

More Pfizer Phase I Results: Antibodies, Viral Mutations, and T Cells

https://blogs.sciencemag.org/pipeline/archives/2020/07/20/more-pfizer-phase-i-results-antibodies-viral-mutations-and-t-cells

I noted in the earlier post that Moderna’s neutralizing antibody data looked best at Day 43, and then went down a bit. These Pfizer/BioNTech numbers look best at Day 29, and have gone down a bit at Day 43. The effect is not huge, but it’s real. The text of the paper says “still increasing up to Day 43”, but that’s not what I see in Figure 2, and I don’t think I would have used that language, myself.


the T cell response looks promising (and probably better than the Moderna candidate)