Brilacidin should be moving up the list. The RBL studies show very positive in vitro activity against Covid 19.
The following have all had disappointing Covid 19 studies published:
Favipirvir,Chloroquine,Acterma,Ritonavir,Remdesivir,Kevsara, Sarilumab.
Cynk-001 Has reported antiviral and anti-inflammatory properties according to the company. I could find not reports of any kind of Coronavirus in vitro studies US studies. Chinese in vitro reports seem without much factual evidence.
BDB-1 Is a monoclonal antibody against complement factor C5a a component of the inflammatory complement cascade. It is reported to decrease inflammmation. The Chinese company is reporting a trial in healthy volunteers was successful and it is to enter clinical trials in Europe.
Rintatolimod is an anti inflammatory previously studied as an AIDS drug. It is approved as a treatment for chronic fatigue in Argentina. It is set to be studied in Argentina and Japan in a Covid 19 trial.
BCG is an old TB accine which may have anti-inflammatory effects.
Ino-4800 Inovio has reported signs of immune response in its Phase 1 trial.
So Brilacidin, a therapeutic,and INO-4800, a vaccine, are the most successful therapies in the list to date.
We will have a better idea where they stand in a few months.
JMO I would be happy to have anyone post additional information on the pharmaceuticals above.
GLTA,Farrell
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