Replies to post #78586 on Cytodyn Inc (CYDY)

[lazyeye]

Agree. The answer lies in the treatment(s), not the vaccine.

If given late at hospitalization, Leronlimab looks like a top choice among many other mid-late stage drugs like Remd and Tocil, or at least has a good enough or better profile to compete very well.

That said, my choice at the hospitalization stage would be convalescent plasma first, if available.

This will all end once a bona fide, non politicized treatment at home BEFORE needing hospitalization is shared worldwide. Right now, it "appears" that HCQ+Azith+Zinc is the front runner if given early and prior to hospitalization.

People will unfortunately still die from this regardless of a treatment or vaccine. Just like every other virus in the world.

[bbaaller42]

Rock, I agree with you to a point. I don't think there will be a vaccine within 12-18 months. However, I do believe there will be a vaccine eventually. As a layperson, the only real comparison for me is the flu. There is a flu vaccine, it works in many cases, but not all cases, because the virus mutates. We know that COVID-19 mutates, and that there are stages to the disease. If you saw Dr. Yang's presentation, you know what I'm referring to. You are right, Cytokine storm is the constant in the moderate to severe cases.

Maybe my post did not adequately reflect my optimism for LERO. Rantes and Cytokine storm are new terms for most of us as well. Dr. Yang showed that LERO reduces the viral load in addition to calming the Cytokine storm. If the current Phase 2/3 trial and this new combo trial with REM shows safety, efficacy, in addition to statistical significance, LERO or LERO/REM will be the go-to mitigation for COVID-19 for an undetermined period of time.

Not to be ignored is that Cytokine storm occurs in other diseases. I'm sure trials will be initiated, if success continues to be demonstrated in COVID-19. I hope you had opportunity to listen to Dr. Lalezari's comments. I never heard any doctor speak in those terms. Essentially he said that Leronlimab was a gift from heaven dropped into our laps. However, as you know better than most of us, we still need to be cautiously optimistic, as potential patients, as loved ones of potential patients, and investors. At this point, IMO, REM needs LERO, more than LERO needs REM.