The scientific literature bolsters NTRP's claim that Bryostatin upregulates PKC-e, which affects BDNF, IGF and NGF. These CNS pathways restore synpapses, clear Amyloid-Beta and Tau, and are neuro-protective.
Neurotrope…today announced that its confirmatory Phase 2 study of Bryostatin-1 in moderate to severe AD did not achieve statistical significance on the primary endpoint, which was change from baseline to Week 13 in the Severe Impairment Battery (SIB) total score.