Replies to post #14135 on General Stock Ideas

[gfp927z]

Ombow, I'll have to check out MBRX. Looking through their recent press releases, I see in late March they announced plans for a $5.25 mil financing on the same day that they made a favorable clinical press release, and now they've done it again in April with a $15 mil financing following a favorable sounding press release.

So they sure don't waste time capitalizing on favorable news. It may look tacky to do that, but at least they 'got the money', which for a micro biotech is essential. They had the shelf registration in place and used it.

Annamycin sounds interesting, though I'll have to do some research. From my 'bio days' I remember that the anthracycline drugs had cardiac toxicity which limited their use, so if Annamycin is truly a safe anthracycline it could conceivably be a big breakthrough. I'll try to catch their webcast tomorrow.


>>> Our Next Generation Anthracycline, Annamycin, is unlike any currently approved anthracyclines, as it is designed to avoid multidrug resistance mechanisms with little to no cardiotoxicity. Annamycin has preliminary clinical data suggesting its potential to become the first successful therapy suitable for the majority of relapsed or refractory AML patients and is currently in two Phase I/II clinical trials. <<<

[gfp927z]

Ombow, Looking at the risks we face as investors, the biggest of all is losing money due to our own bad judgement -


1) Bad judgement/decisions

2) Market volatility

3) Financial crises

4) Geopolitical events

5) Natural disasters


Category #1 includes just about everything done here on I-Hub - trading, chasing 10 baggers, micro/penny stocks, etc.

John Bogle's approach (founder of Vanguard) is to avoid individual stocks (use broad index funds/ETFs), and avoid market timing (use buy/hold).Risk (and emotions) are managed via the asset allocation (% in stocks vrs bonds). It's a slow but reliable way to build wealth, and not only minimizes risk but reduces taxes and transaction fees.

But it's boring, so if your main hobby is following stocks, I figure you can still do individual stocks with a small amount like 5%.

As Bogle said, if you're worried about the market/world, reduce your stock allocation and increase the % in bonds and gold/hard assets. Right now my target allocation is 45% stocks, 50% bonds, 5% gold, and my dad's (91 years old) is 30% stocks, 65% bonds, 5% gold.

No allocation is perfect, but if the stock market crashes 50% tomorrow, we would only be down 22.5% and 15% respectively, so not the end of the world, and the bonds/gold would probably be up during that period.

With a limited amount (5%) I can piddle around with individual stocks and not jeopardize the overall goal. The worst thing you can do is to gamble with large amounts in the market. Don't do it - been there done that..