Algernon Pharmaceuticals Key Research Milestone Summary
Annual Information Form
For The Financial Year Ended August 31, 2018
April 11, 2019
Page 28
1. November 1, 2018 – Company Announces Positive Pre-Clinical Results Showing Lead Compound NP-160 Significantly Reduces NALFD Score and Fibrosis in Non-Alcoholic Fatty Liver Disease. 2. November 5th, 2018 - The Company announced that it amended its research agreement with the University of Florida’s Analytical Chemistry Department to finalize development of the FAIMS working prototype device. 3. November 13, 2018 - Company Announces Positive Pre-Clinical Results For Its Lead Compound NP-178 in Inflammatory Bowel Disease. 4. November 19, 2018 - Company Announces Positive Pre-Clinical Results For Its Lead Compound NP-135 in Chronic Kidney Disease. 5. December 3, 2018 – Company Announces Positive Pre-Clinical Results For Its Lead Compound NP-178 in a New Study for Crohn’s Disease. 6. January 14, 2019 – Company Announces Positive Pre-Clinical Results From a Second Study for Chronic Kidney Disease as well as two Additional Lead Targets. 7. January 21, 2019 – Company Announces 84% Reduction of Fibrosis by Additional Lead Compound In Second Pre-Clinical Study For Non-Alcoholic Fatty Liver Disease. 8. February 25, 2019 – Company Expands Its Research Program to Include Idiopathic Pulmonary Fibrosis.