Dew, Safety of MM-093 yet to be established, of course safety of AFP at least intrinsic AFP tested on millions of child bearers who seem to have done well! What is behind your (hopefully correct) supposition that this agent should be safer than Enbrel et. al.?? I recently saw a patient who had been on Enbrel for over three years with great inprovement in her RA but unfortunately developed disseminated histoplasmosis (which I know little to nothing about) but my pulmonary consultant has seen a few. If AFP were safer in this regard it would indeed fit floblu's definition of bombshell (in the positive sense). Again hats off to floblu for great IP updates and for helping to pry open the Merrimack wall of silence. And to Dew's insights which have prevented (thus far) my entry into the assylum as I have watched this wonderful and promising stock decend into the land of goat goo (at least lately), but as they say one man's goo is another man's treasure...regards, bp
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