So we know that the formulation of P467-CRM Montanide induced higher serum lgG antibody tilers, compared with P467-CRM Alum.
The formulation P467-CRM-Montanide has recently been examined in a toxicology study and shown no signs of toxicity or inflammation when evaluated in dogs and rats (data not shown). A doseescalating study, starting with 10 µg of the formulation, is being planned to be evaluated in a phase-Ib/II clinical trial enrolling Her-2/neu overexpressing cancer patients