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Replies to post #253862 on Innovation Pharmaceuticals Inc (IPIX)
01/11/19 9:29 AM
According to Future Medicine, annual costs associated with treating all types of mucositis in approximately 522,000 patients annually total $13.23 billion.
Galera has managed to raise over $250 million in the last six years, including $150 million in equity and royalty deals ($80 million which was based on future sales of CG4419) about three months ago. Galera has rallied plenty of support from venture capital, with financing partners including Clarus Ventures, Adage Capital Management, Novartis Venture Fund and more.
In the Galera trial, treatment with GC4419 in the higher cisplatin group reduced the relative incidence of SOM by 41% compared to placebo in the Intent-to-Treat (ITT) population. In the ITT – IMRT (intensity-modulated radiation therapy) population, the relative incidence of SOM decreased by 39% versus placebo.
In the IPIX trial, treatment with Brilacidin in the modified Intent-to-Treat (mITT) population reduced the relative incidence of SOM by 65.0% compared to placebo. In the Per Protocol population, the relative incidence of SOM decreased by 80.3% compared to placebo
An oral therapy can be a double-edged sword. One, it can have a competitive edge as oral drugs are the preferred method of administration for patients compared to laying there while the drug slowly drips through an IV. To that point, an oral drug is far more convenient, with administration available in an array of settings compared to IV. It also less expensive, likely making it the preferred method of not only insurance companies, but also doctors writing the prescriptions.
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