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dodah_2

11/06/06 7:48 AM

#1757 RE: DewDiligence #1736

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DewDiligence

11/28/06 4:11 PM

#2045 RE: DewDiligence #1736

>Another potential DIC/sepsis competitor is Tifacogin, which NVS picked up when it acquired Chiron earlier this year. Tifacogin failed in a phase-3 sepsis trial in 2001, and hence I had assumed that the compound was dead. However, NVS might be attempting to resuscitate this compound for sepsis. I’ll pay attention to anything that may be revealed at NVS’ R&D Day on Nov 28.<

Oddly, the Tifacogin program appears to have been expedited. NVS’ webcast slides today show it as a planned NDA submission in 2008, a year earlier than NVS’ prior presentation materials. I will attempt to get clarification.