Replies to post #2315 on Dynavax Technologies Corp (DVAX)

[jondoeuk]

I'm hoping they put the TLR7/8 agonist into the clinic soon. In this preclinical study, they show the combination of both has a synergistic effect https://jitc.biomedcentral.com/articles/10.1186/2051-1426-2-12 Treating extremely large tumours of this size is generally considered futile.

Also, if DV281 pans out adding on an inhaled TLR3 agonist should enhance the efficacy of it https://www.tandfonline.com/doi/full/10.1080/2162402X.2015.1040214