Replies to post #78727 on Ayala Pharmaceuticals Inc (fka ADXS)

[DewDiligence]

Would [ADXS] not they need a pre-clinical dataset for a specific PD-1/PDL-1?

Pre-clinical data in support of the HOT IND with one of the FDA-approved checkpoint inhibitors probably suffices for a phase-1 study with any of the four FDA-approved checkpoint inhibitors because the checkpoint inhibitors are so similar to each other.