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frrol

02/10/18 11:21 AM

#216858 RE: To infinity and beyond! #216850

Correct, he would have. There were some instances of disease stability and even regression in the Phase 1, but nothing you could hang your hat on. Folks were skeptical given the half-life and dosing regimen, understandably so. Some here felt the Phase 1 'proved' efficacy, but cancers are too unpredictable to assume that.

Our management is promotional (rightly so), so when they don't say something it's often a purposeful omission. There was no mention of tumor response in the limited Phase 2A; it is very reasonable to infer there was none. You don't completely halt a trial that was successfully treating a deadly condition. These guys wouldn't for that reason and more.