Replies to post #207376 on Innovation Pharmaceuticals Inc (IPIX)

[MinnieM]

As a patient, I'd be clamoring for Brilacidin as a potential preventative of severe OM.

Oddly, it seems that the incidence of OM in the placebo group was a bit low.

http://www.sciencedirect.com/science/article/pii/S0168165616315668#bib0025

Severe OM (SOM) occurs in almost 75% of these patients and is among the most debilitating and painful side effects related to treatment (Elting et al., 2009). SOM is associated with increased opioid use, weight loss, reliance on supplemental feeding and hydration, breaks in treatment, unplanned office, or emergency room visits and frequent hospitalizations resulting in an incremental cost of $18,000 per patient (Nonzee et al., 2008).

[petemantx]

Are P3 trials normally open labeled or will we have to go thru the placebo arm again?