CP, UTSW did file such an application...the questions you raise will be the subject of patent application prosecution in the various patent offices where application is pending...one of such patent offices will take the lead in accord with national laws and treaties extant.
In a quick skim of the full specification and claims, the application seems to embrace/comprise the entire waterfront insofar as Dr. Schroit's[et al] discoveries that I have seen so far.
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