Replies to post #314090 on Avid Bioservices Inc (CDMO)

[biopharm]

Peregrine RNA-Seq library

Stanley A. Langevin, †
Zachary W. Bent, †
Owen D. Solberg,
Deanna J. Curtis,
Pamela D. Lane,
Kelly P. Williams,
Joseph S. Schoeniger,
Anupama Sinha,
Todd W. Lane, and
Steven S. Branda*

https://www.researchgate.net/publication/304821888_Experimental_single-strain_mobilomics_reveals_events_that_shape_pathogen_emergence

Top co-authorsView all
Steven S Branda
Steven S Branda
29.63 (9)Sandia National Laboratories
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Douglas Faller
Douglas Faller
45.62 (7)Boston University
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Gerald V Denis
Gerald V Denis
34.42 (7)Boston University
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Kelly P Williams
Kelly P Williams
38.08 (5)Sandia National Laboratories
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Zachary Bent
Zachary Bent
21.39 (4)

..... There seems to be lots of patents evolving out of Sandia National Labs and I would like Peregrine to clarify all the non Disclosed collaborations because I still stick with any and all groups that had access to PS Targeting data are realizing AFTER ....what was non obvious BEFORE access to PS Targeting research/data ...what protein pathways to concentrate on and much more....

We have Patents by Inventor Joseph S. Schoeniger which may be part of new knowledge ...after such new data learned with "Peregrine RNA-Seq library "

Methods and materials for deconstruction of biomass for biofuels production
Patent number: 9024111
Abstract: The present invention relates to nucleic acids, peptides, vectors, cells, and plants useful in the production of biofuels. In certain embodiments, the invention relates to nucleic acid sequences and peptides from extremophile organisms, such as SSO1949 and Ce1A, that are useful for hydrolyzing plant cell wall materials. In further embodiments, the invention relates to modified versions of such sequences that have been optimized for production in one or both of monocot and dicot plants. In other embodiments, the invention provides for targeting peptide production or activity to a certain location within the cell or organism, such as the apoplast. In further embodiments, the invention relates to transformed cells or plants. In additional embodiments, the invention relates to methods of producing biofuel utilizing such nucleic acids, peptides, targeting sequences, vectors, cells, and/or plants.
Type: Grant
Filed: March 30, 2012
Date of Patent: May 5, 2015
Assignee: Sandia Corporation
Inventors: Joseph S. Schoeniger, Masood Zia Hadi

https://patents.justia.com/inventor/joseph-s-schoeniger

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The only way to gather ALL the information is to know ALL non disclosed collaborations and then sifting through ALL patents by the collaborating parties.....opportunities exist to target flipped PS in many places and Peregrine should be capitalizing on all such collaborations and hope to hear more about revenue streams that we have been left in the dark in....and clearly exist and easy to see.

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Lipid remodelling: Unravelling the response to cold stress in Arabidopsis and its extremophile relative Eutrema salsugineum
Author links open overlay panelCristinaBarrero-Sicilia12SusanaSilvestre1Richard PHaslamLouise VMichaelson
Plant Sciences, Rothamsted Research, West Common, Harpenden, AL5 2JQ, UK
Received 24 April 2017, Revised 20 June 2017, Accepted 12 July 2017, Available online 27 July 2017.

Highlights
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Higher plants rapidly remodel cellular lipids in response to environmental perturbation and abiotic stress.

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Lipids in plants perform many important functions including information exchange, protection, energy storage, signalling and light capture.

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Increases in unsaturation are a common response to cold stress, but not the only mechanism of adaptation.

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An increased understanding of lipid turnover is essential to establish the contribution made by the lipidome to plant stress resilience.
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Opportunities exist to improve the resilience of crops by manipulating the lipidome.

Abstract
Environmental constraints limit the geographic distribution of many economically important crops. Cold stress is an important abiotic stress that affects plant growth and development, resulting in loss of vigour and surface lesions. These symptoms are caused by, among other metabolic processes, the altered physical and chemical composition of cell membranes. As a major component of cell membranes lipids have been recognized as having a significant role in cold stress, both as a mechanical defence through leaf surface protection and plasma membrane remodelling, and as signal transduction molecules. We present an overview integrating gene expression and lipidomic data published so far in Arabidopsis and its relative the extremophile Eutrema salsugineum. This data enables a better understanding of the contribution of the lipidome in determining the ability to tolerate suboptimal temperature conditions. Collectively this information will allow us to identify the key lipids and pathways responsible for resilience, enabling the development of new approaches for crop tolerance to stress.
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http://www.sciencedirect.com/science/article/pii/S016894521730362X

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