No. I never plan on using thrombin. I use it when I stick the needle in Co-axially and blood spurts out. I am more worried about life threatening hemorrhage than bovine thrombin antibodies forming. As an aside I just got off the phone with a very busy vascular surgeon. He uses bovine thrombin almost daily and on the same patients multiple times due to reoperations. He estimates he has used it 2-3000 times in his surgical career. He has never seen an allergic reaction or even thought about it (probably because it is used topically soaked into gelfoam on the bypass grafts) nor has he ever heard from collegues or at meetings of a significant reaction or even read about one. He did concede there is probably literature floating around about it.
Let me tell you severe reactions of any kind get looked at very critically in a hospital setting so I can't believe we are somehow "missing them". I am just not convinced this is a big deal clinically. However, I think this a lock to get approved, as my friend the surgeon said "why wouldn't it be approved"? So then my question is the 1.1 Billion dollar market cap full valuation or is there significant upside? (I suspect there will be upside to the stock)
Proctor and Gamble sells alot of Scope mouthwash even with its dubious efficacy.