What percent of the Ifosfamide is converted by the 200K cells inside CIAB vs approx 4.5B liver cells?
Can anyone answer this?
Why doesn't the ifosfomide get triggered by the liver before it reaches the tumor? Has it been modified in some way to only be triggered by the cells inside ciab?
Is it that it is triggered by both but because of the smaller doses and the triggering right next to the tumor that the effect next to the tumour is still strong enough to be effective?