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Maple tree

02/16/17 5:44 PM

#846 RE: Maple tree #845

Like this statement in the article: Neurotrope's bryostatin was developed through a focus on PKC epsilon - an enzyme which has been shows to be at a deficit in brains of AD patients. "It's not just restoring the synaptic networks, it's actually preventing the cascade of biochemical events whereby the neurons actually die. And PKC epsilon stimulated by bryostatin actually inhibits that, it prevents neuronal death and then in addition it stimulates synaptic growth. Those two things are unique."
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bUrRpPPP!

02/16/17 5:57 PM

#847 RE: Maple tree #845

Neurotrope holds around 70 patents on its bryostatin and even more importantly, the rights to use PKC epsilon for treatment of AD. Alkon put it this way, "Suppose somebody else, let's say Lilly, came up with a new PKC epsilon activator, and let's say that it had good efficacy. The drug they came up with would be theirs, but to use it to treat Alzheimer's they'd have to work with us." And of the prospect of teaming up with pharma partners? "We'd be happy to work with them."