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biopharm

01/28/17 6:32 AM

#284674 RE: Protector #284673

I would think Dr Patrick Soon....would want such cost savings and to secure PS Targeting under the umbrella of one of his many biotech startups or create a new one...

Just another possible option / path for Peregrine, and he is one that would probably want the rs to happen but I would think they can come up with a creative plan

Maybe Sean Parker should just make a move and don't let any more time go to waste.....all of Parker Institute will need PS Targeting
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geocappy1

01/28/17 6:50 AM

#284676 RE: Protector #284673

I think running one test to rule out cancer would be important. If negative great. If positive, run other tests to determine which type cancer it might be.
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unpathedhaunt

01/28/17 7:42 AM

#284678 RE: Protector #284673

Thanks very much, CP, for the explanation.
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cheynew

01/28/17 8:10 AM

#284679 RE: Protector #284673

I'd be very interested in hearing from the science guys about what competition there is in the exome-based testing area. It certainly looks like PPHM could have a slam dunk here, but are there other tests in the works that might be as good?
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sunstar

01/28/17 12:23 PM

#284692 RE: Protector #284673

With respect to exosome testing, PPHM has published "Highly Specific PET Imaging of Prostate Tumors in Mice with an Iodine-124-Labeled Antibody Fragment That Targets Phosphatidylserine."

Images of tumor location show clearly in a PET scan. Any metastases should also be evident in a scan.

http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0084864&type=printable

Exosome test tells doctors/patients that there is a significant quantum of PS-positive exosomes in the patient's system. The next step would be a conformational and locational scan.

Peregrine ran a human trial at Washington University School of Medicine, started June 2012, and closed out on schedule, March 2016. Peregrine has that data.

"Open-label, Single Arm, Tumor Imaging and Dosimetry Study of I-124 PGN650 in Advanced Solid Tumors"

https://clinicaltrials.gov/ct2/show/NCT01632696?term=peregrine+pharmaceuticals&rank=14

The high value of the "Detection of phosphatidylserine-positive exosomes as a diagnostic marker for ovarian malignancies" is the ability to diagnose this ovarian tumor type at an earlier stage than has been previously possible. It should be a real lifesaver for many women in the future of ovarian oncology.

IMO

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