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ciotera

01/17/17 9:09 PM

#208100 RE: jq1234 #208097

Re: MYSTIC PD-L1 cutoff

And here also they don't really have much choice.
CM012 showed that Nivo+Ipi worked in PD-L1 positive (1%+) but fell short in PD-L1 negative. So, I think we should read the PR language literally "PD-L1 expressing" = any expression. Of course, they could play it safe and set it at 5 or 10%, but even BMY isn't doing this (after getting burned on CM024).