The ad hoc European tests confirmed lower dose Ifosfamide has lower toxicity than higher dose Ifosfamide.
also that Ifosfamide under low doses does work BETTER with CiaB holding cells directly at the tumor site
And what were the results of the low dose control arm of just Ifosfamide without CiaB? There was no such control arm in the study. There is no basis for saying it's "BETTER".
It's actually common sense and simple for most to understand.
So should the concept of requiring control arms in a drug study.