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loparn

11/13/16 3:12 PM

#206014 RE: mcbio #206012

WntResearch, WNT.ST is an example of an extremely fine risk/reward in a Phase Ib-project Foxy-5

http://www.infoom.se/mysite/index.php?sida=80579&user=9801

Sooner or later the market will understand why Foxy-5 could be the first antimetastasis drug ever.

These Kaplan-Meier-curves comparing Foxy-5:s "target" molecule Wnt-5a in breast cancer patients show the potential http://cancerres.aacrjournals.org/content/canres/62/2/409/F6.large.jpg?width=800&height=600&carousel=1
...if Foxy-5 could do the same in patients with low or no Wnt-5a expression in their primary tumors.

The curves show a difference of over 8 years in progressionfree median survival depending on the natural Wnt-5a expression.

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bladerunner1717

11/13/16 4:01 PM

#206015 RE: mcbio #206012

McBio,

Don't worry about the macro factors; the're all on the side of a biotech explosion, Clark's over-cautiousness notwithstanding. Just ask Clark what exactly he means by "temporary" in his phrase "the boost will be temporary". Force Clark to define "temporary" in quantitative terms. (He's really good at that.)

My guess is that we will have tremendous growth in biotech for, at least, the next three or four years, assuming The Donald doesn't do anything really stupid on trade, on the FED or on the geo-political front or trying to go after Hillary.

I'll even predict that Trump's stimulus plan (written by Peter Navarro) gets more Democratic support than Republican support. See this article from Bloomberg (with my notes):


Trump Adviser Takes Aim at Conservatives’ Budgetary Restraint

Christopher Condon chrisjcondon
November 12, 2016 — 10:06 AM PST


Infrastructure spending needed, not fiscal austerity. (WOW!!! Is this Republican conservative channeling Paul Krugman?)

Don’t expect President-elect Donald Trump to adhere consistently to traditional Republican economic policy, or even to positions Trump staked out during his election campaign.
That’s the message in an opinion piece written in the Financial Times by Trump economic adviser Anthony Scaramucci that took a swipe at the budgetary discipline promoted for years by fiscal conservatives in the U.S. and Europe. It may point to a coming rift between the new executive branch and the Republican-controlled Congress. (The incredible irony here, of course, is that more Democrats than Republicans may vote for Trump’s fiscal stimulus plan.)

“Mr. Trump is a different type of leader not burdened by rigid ideology,” Scaramucci said. “He is not dogmatic about policy positions. Rather, he has set bold targets from which to begin negotiations.”

Scaramucci ran though some of Trump’s previously-announced plans, including a proposal for a 10-percent one-off repatriation fee for companies. Trump would “ideally” like to see corporate tax rates cut to 15 percent from 35 percent, he said, adding that even a reduction to equal the U.K. rate of 20 percent would add nearly $600 billion to U.S. GDP.

Founder of the investment firm SkyBridge Capital, Scaramucci, 52, was named on Friday to the executive committee of Trump’s transition team. The 16-person list also includes Dune Capital Management chief executive officer Steve Mnuchin, who was finance chairman of Trump’s campaign; Reince Priebus, chairman of the Republican National Committee; and three of the president-elect’s children.

Battling Deflation
Scaramucci said global economies are still battling deflation largely because of a movement toward fiscal austerity that followed the 2008-2009 global economic crisis.

“While easy-money monetary policies have exacerbated the income divide, central bankers handcuffed by political dysfunction have had little choice but to provide extraordinary accommodation,” he said. “Business people like Mr. Trump understand you can grow yourself out of excessive debt.”

Trump, who said early in his campaign that he liked low interest rates, later became critical of the Federal Reserve’s low-rate policies. In September, he accused Chair Janet Yellen of keeping rates low to benefit President Barack Obama. Yellen’s time as chair ends in 2018, unless she’s reappointed. Trump will also be able to appoint two senior Fed officials to fill vacancies on the Board of Governors. (Does this mean that Trump will appoint more “doves” to the Board? Interesting question, because Trump is not a deficit-hawk. Remember, Trump is the “King of Debt.” Then there is the whole question of the newer theories of “Market Monetarism,” wherein GDP growth would be taken into account by the FED. This is a much more dovish position than traditional conservatives and deficit-hawks on the FED Board take. There is a crazy, ironic reversal, if Trump follows through on these proposals. This could really goose the economy and especially the Markets—Blade)

Another Trump economic adviser, Judy Shelton, said on Bloomberg Television on Friday that Trump’s administration will respect the Fed’s independence.

Softening on Trade?
Scaramucci repeated Trump’s pledge to spend $1 trillion on infrastructure “financed by historically cheap debt and public-private partnerships,” and said the plan would lower long-term deficits. LOL He sounded a softer note on trade than Trump had declared on the campaign trail, suggesting the president-elect is open to negotiations before slapping barriers on imports.

“Mr Trump believes in free-but-fair trade. Tariffs are unnecessary if agreements like the World Trade Organization and Nafta are adequately enforced,” Scaramucci said, referring to the global treaty on trade as well as the North American Free Trade Agreement that Trump regularly excoriated on the stump.

In other ways, the outline Scaramucci provided sticks to the traditional Republican playbook and to Trump’s campaign rhetoric. He attacked regulation in general as a growth killer, and took specific aim at the burden put on small companies by the Affordable Care Act, as well as restrictions under the Dodd-Frank Act that Scaramucci said had scaled back lending by banks.


Additionally, Scaramucci suggested Trump would seek to reverse a recent Labor Department ruling that requires brokers to put clients’ interests ahead of their own when handling retirement investments.

Scaramucci said Trump’s plan to cut the corporate tax rate to 20 percent from 35 percent would add 3.3 percent to gross domestic product.
The article appeared as Trump and his team began to offer more details of his intended policies, in some cases appearing to retreat on promises made during the campaign.

In an interview scheduled to air Sunday on “60 Minutes,” Trump reversed himself on completely eliminating the Affordable Care Act, President Barack Obama’s signature health law, saying instead he would keep two popular features and pledged no gap in coverage as it’s replaced or amended.


Bladerunner