Replies to post #545 on Dendreon Corp fka DNDNQ

[poorgradstudent]

1. No trp-p8 association:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=12086878&...

It's newton's law of pubmed... for every citation, there is a citation of equal magnitude in the opposite direction.

I think it is also clear from years of gene array that changes in gene expression in the absence of robust (not singular) protein expression analyses are not overly useful.

>The data presented show that these potent agonists of Trp-p8 significantly inhibited the growth of Trp-p8 positive tumors in mice by as much as 77 percent over controls (p=<0.0001).<

If this is valid and exciting, perhaps you can explain what types of tumours these were, etc... The AACR abstract gives no detail, and DNDN's PR in this provides no detail. I don't see how this proves anything one way or the other since the result can not be studied or critiqued in detail.