Replies to post #266459 on Avid Bioservices Inc (CDMO)

[jakedogman1]

don't know the genesis of the trial...

and don't know whether the trial starts up again given it's phase 2...

or whether some other entity aka BP takes the reins or whether it's modified with I-O....

what we do know is pphm has rightfully given up conducting larger trials.... too expensive for the current state of the company and they really don't have the clinical horsepower or "star" power that a bp has in attracting patients... all imo

check out the other BC trial... suspended and updated march 8...

Taxane Therapy With or Without Bavituximab for the Treatment of HER2-Negative Metastatic Breast Cancer

whereas the Study of Neoadjuvant Paclitaxel in Combination With Bavituximab in Early- Stage Triple- Negative Breast Cancer is not yet recruiting and was updated feb 17..

we do know pphm is somewhat sloppy in updating trial info...

[jakedogman1]

one other thing to consider is this:

5-11-16/Breast Cancer Research: “Phosphatidylserine-targeting Antibodies Augment the Anti-Tumorigenic Activity of Anti-PD-1 Therapy by Enhancing Immune Activation & Downregulating Pro-Oncogenic Factors Induced by T-Cell Checkpoint Inhibition in Murine Triple-Negative Breast Cancers”
http://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-016-0708-2


http://investorshub.advfn.com/boards/read_msg.aspx?message_id=122583004

so my guess is the powers that be would want the pd-1 angle played before chemo