Replies to post #259731 on Avid Bioservices Inc (CDMO)

[biopharm]

Funding Opportunity Number: EP-IDS-16-001

Funding Opportunity Title: Combating Antibiotic Resistant Bacteria (CARB) Biopharmaceutical Accelerator

Eligible Applicants:
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public and State controlled institutions of higher education

http://www.grants.gov/web/grants/search-grants.html?keywords=EP-IDS-16-001

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Think of a grant like this, where a dozen top cancer institutions with direct access to PS Targeting could capture Millions in funding. $2 Million from Peregrine can turn into $30 Million per Institution. You think all this sparks some debate in Big Pharma and pits the top researchers against one another, pits Big Pharma vs Big Pharma... I do.

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The rise of antibiotic-resistant bacteria represents a serious threat to public health and the economy. Detecting, preventing, and controlling antibiotic resistance requires a strategic, coordinated, and sustained effort. The federal government will work domestically and internationally to detect, prevent, and control illness and death related to antibiotic-resistant infections by implementing measures that reduce the emergence and spread of antibiotic-resistant bacteria and help ensure the continued availability of effective therapeutics for the treatment of bacterial infections.

In March 2015, the U.S. Department of Health and Human Services (HHS) announced the establishment of the Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (Advisory Council). The Advisory Council will be governed by provisions of the Federal Advisory Committee Act, Public Law 92-463, as amended (5 U.S.C. App.), which sets forth standards for the formation and use of federal advisory committees.

The Advisory Council provides advice, information, and recommendations to the Secretary regarding programs and policies intended to support and evaluate the implementation of Executive Order 13676, including the National Strategy for Combating Antibiotic-Resistant Bacteria (Strategy) and the National Action Plan for Combating Antibiotic-Resistant Bacteria (Action Plan).

On September 15, 2015, the U.S. Department of Health and Human Services, the U.S. Department of Agriculture (USDA), and the U.S. Department of Defense (DoD) announced the appointment of nationally recognized experts to the Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (the Advisory Council).

http://www.hhs.gov/ash/carb/

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Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance

Fernanda Guilhelmelli1†,
Nathália Vilela1†,
Patrícia Albuquerque1,
Lorena da S. Derengowski1,
Ildinete Silva-Pereira1 and
Cynthia M. Kyaw2*

1Laboratório de Biologia Molecular, Departamento de Biologia Celular, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, Brazil
2Laboratório de Microbiologia, Departamento de Biologia Celular, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, Brazil

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Main Mechanisms of Action

The classic action mechanism of AMPs involves their ability to cause cell membrane damage. AMPs can interact with microorganisms by electrostatic forces between their positive amino acid residues and negative charges exposed on cell surfaces. It has been suggested that the composition of cell surface drives the specificity of AMPs.

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http://journal.frontiersin.org/article/10.3389/fmicb.2013.00353/full

The hell with the current price of PPHM

The hell with the current modulated negativity

Look forward to the future price of PPHM

Look forward to all those holding non-disclosures agreements, being able to speak openly on how big PS Targeting truly will become

Now back to the usual one liners that show up daily, for some reason... to save you from holding PPHM or buying PPHM and think about motives