Replies to post #117285 on NanoViricides Inc (NNVC)

[drkazmd65]

:-D

[KMBJN]

Welcome back! Your statement is bullshit:

"The 45,000 people per year who get the disease need to get it from UNCURED people for the most part otherwise the numbers diminish to zero."

Reality is that >60% of people (~200M in the US) are infected with HSV-1, and it remains latent in their trigeminal ganglia. When the immune system is weakened, the virus breaks out, causes oral herpes (cold sores), and the virus can then spread to the eye, thus causing herpes keratitis.

Same with the chickenpox / shingles (HHV-3) and genital herpes (HSV2/HHV-2). The virus remains latent and the goal is to keep it suppressed or to treat outbreaks to lessen their severity. The goal also is to prevent spread to others, to reduce asymptomatic viral shedding.

Herpes is expected to be a multi-billion dollar market.

Here's one overview just for HSV-2:

http://www.dddmag.com/articles/2015/07/herpv-gen-003-will-drive-genital-herpes-treatment-market-growth-2023

HerpeCide could be a hugely successful franchise, and NNVC may keep it all to themselves, per the last ASM.

Some vaccines are in development (like Genocea's GEN-003, and HERPV), but they haven't really been shown to work much better than placebo just yet, as far as I've seen.

Treatment and prevention is primarily acyclovir, which I heard goes generic this year.

[JG36]

(4) If we ran with the laughable ASSumption that everybody with a disease got cured by NNVC, there would be little if anybody left the following year to cure! The 45,000 people per year who get the disease need to get it from UNCURED people for the most part otherwise the numbers diminish to zero.

While your other criticisms are legitimate, this one isn't. The virus in ocular herpes is the same one in cold sores. Instances of ocular herpes typically happen when people accidentally transmit viruses from a cold sore to their eyes. So if every instance of ocular herpes was cured there would still be plenty more instances the next year. It's highly unlikely that the herpes virus will be wiped out in its entirety.