Replies to post #197905 on Biotech Values

[DewDiligence]

ABBV/ENTA—Is this a non-issue for GT4, or GT1b in Japan?

Non-issue because ABBV/ENTA’s approved regimens for GT4 patients (Technivie) and GT1b patients in Japan (Viekirax) do not contain Dasabuvir and hence are already dosed qD.

[DewDiligence]

It is not uncommon that ribavirin dosing can be reduced due to AE's. Mine was cut in half, from 1200mg to 600mg (6 pills to 3 pills) due to anemia… In a dose reduction scenario, one could [take ribavirin] just once per day.

A valid point. Ribavirin is generally dosed BID for tolerability, not for efficacy.