The options in question did not expire until 2021.
The last time Luly did an exercise-and-hold maneuver was in Oct 2015—right after the big drop in the share price due to the V-Pak label change (#msg-117951247).
Moreover, ENTA’s CSO executed exercise-and-hold transactions on $4M worth of stock in Jan 2016 (#msg-119968598).
Please see the thread culminating in #msg-109711695 for related info.