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Amatuer17

10/16/15 8:48 AM

#126059 RE: frrol #126058

Here is the list

Membrane-active small molecules undergoing clinical trials.

Compound- indication - phase - company

Brilacidin - Oral mucositis- Phase II- Cellceutix, USA

Brilacidin - Skin infections (ABSSSI)- Phase II Cellceutix, USA

LTX-109 - Impetigo - Phase II - Lytix Biopharma, Norway

LTX-109 - Nasal decolonization - Phase II - Lytix Biopharma, Norway

LTX-109 - Diabetic foot ulcers - Preclinical - Lytix Biopharma, Norway

CSA-13 - Cystic fibrosis - Preclinical Medical – N8 medical USA
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slcimmuno

10/16/15 9:06 AM

#126060 RE: frrol #126058

Have to say that article is the best overview of the true potential of Brilacidin and analogs I've come ever across. They covered everything. A very compelling read.

Was nice to see the PYMX research by DeGrado, Tew, ref'd across multiple pages--CTIX def standing on the shoulders of giants in the field, all their great early work coming closer to fruition.

Am also glad to see folks on the board back to discussing the Science.

(A-17 just posted the list of drugs in current trials.)

Below a link to a blog post by the ex-industry guy Shales who org'd next week's ABX Congress where Menon is presenting. Some good inside dope on regulatory differences btw EMA and FDA. Pathogen-spec trials.

Anyway, Here's hoping the ABX provisions 21st Century Cures remain and some version of the law gets passed.

http://antibiotics-theperfectstorm.blogspot.com/2015/10/fda-roche-polyphor.html