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DewDiligence

12/03/15 4:55 PM

#197935 RE: DewDiligence #195033

PTLA selling 2.99M* shares at unspecified price:

http://finance.yahoo.com/news/portola-pharmaceuticals-announces-proposed-offering-213511578.html

Not the best timing, perhaps, but PTLA does need money.

*Assuming exercise of underwriter’s option.

DewDiligence

12/18/15 10:32 AM

#198389 RE: DewDiligence #195033

PTLA completes BLA submission for Andexanet Alfa (FXa reversal agent):

http://finance.yahoo.com/news/portola-pharmaceuticals-completes-bla-submission-130000329.html

The name, Annexa A, which PTLA had used in prior investor communications, has apparently been discarded.

Please see #msg-116997511 for background info on the phase-3 and phase-4 program for this drug.