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md1225

08/22/15 7:20 AM

#231343 RE: biopharm #231332

Late Breaking? 12 noon 8/26 not announced yet? Dr. Hutchins chairman? Maybe just maybe....
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biopharm

04/11/17 8:52 PM

#294654 RE: biopharm #231332

Jerry McMahon, Ph.D., President & CEO, Kolltan Pharmaceuticals

TAM receptor tyrosine kinases and their cognate ligands play a key role in immune homeostasis through signaling in macrophage and dendritic cells and regulating the adaptive immune response. Modulation of the activation of these receptors may up- or down-regulate immune homeostasis for the treatment of cancer and other diseases. Inhibition of Axl and MerTK are under investigation to potentiate the effectiveness of biologic agents that interfere with T cell checkpoints in tumor immunology.



Kolltan collaborating with Peregrine Pharmaceuticals by connecting these dots...

The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer
http://www.nature.com/nrc/journal/v14/n12/full/nrc3847.html