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Replies to #30154 on Biotech Values
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Hacktheripper

07/12/06 1:48 PM

#31229 RE: DewDiligence #30154

Halted --->13:40 GILD Gilead Sciences: FDA Spokesman confirms approval of triple AIDS pill- bloomberg (61.84 +0.08)

(note stock is halted)



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DewDiligence

10/28/06 6:16 PM

#36424 RE: DewDiligence #30154

Tyzeka vs Hepsera, Part Two
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#msg-11594768 showed data from the first 24 weeks of the phase-3b head-to-head study of Tyzeka (telbivudine) vs Hepsera (adefovir). The result: Tyzeka won easily, logging a mean viral-load reduction of 6.30 logs vs 4.97 logs for Hepsera at 24 weeks.

At 24 weeks, half of the Hepsera patients in the trial were switched to Tyzeka and thus there were three arms: Tyzeka for 52 weeks, Hepsera for 52 weeks, and the switch arm consisting of Hepsera for 24 weeks followed by Tyzeka fro 28 weeks.

The chart above shows the % of patients in each arm with undetectable virus at each time point.