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Replies to #29356 on Biotech Values
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Biowatch

09/29/18 6:09 PM

#221142 RE: DewDiligence #29356

Hep B vaccine non-responders and infection

I've heard that the hepatitis B vaccine is less likely to help Asians (i.e., they may be "non-responders.")

This may reflect the fact that the vaccine probably won't help people already infected with Hepatitis B.

https://www.cdc.gov/hepatitis/populations/api.htm
Quote:
Key Facts

Asian Americans and Pacific Islanders (AAPIs) make up less than 5% of the total population in the United States, but account for more than 50% of nearly one million Americans living with chronic hepatitis B.

The burden of chronic hepatitis B in the US is greater among people born in regions of the world with high or moderate prevalence of chronic hepatitis B, including much of Asia and the Pacific Islands.

Nearly 70% of Asian Americans are foreign-born and estimates have found that approximately 58% of foreign-born people with chronic hepatitis B are from Asia [And the other 42% are...?]

Left untreated, approximately 15% to 25% of those with chronic hepatitis B infection develop serious liver disease, including cirrhosis, liver damage, and even liver cancer

Asian Americans and Pacific Islanders are 8-13 times more likely to develop liver cancer than other groups, primarily due to hepatitis B infection

The liver cancer death rate is 60% higher for Asian Americans and Pacific Islanders than Caucasians