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biocqr

04/21/15 1:32 PM

#190257 RE: backstroke_ #190254

AAVL have a license with UC for that



The 4DMT web site mentions a license from UCB to AAVL for LCA congental blindness...

http://dmt.wpengine.com/technology/directed-vector-evolution/

Is that what you are referring to? If so, why no mention of an LCA program on AAVL's latest investor presentation.
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mcbio

04/21/15 9:54 PM

#190265 RE: backstroke_ #190254

AAVL

Yes intravitreal clearly better, AVA-201 is intravitreal. 201 is supposed to use a next-gen vector and they also talk about directed vector evolution, AAVL have a license with UC for that.

Makes me even more inclined to await further data on 101 before considering AAVL as sounds like 201 might be a better drug (I know going after wet AMD prevention versus treatment with 101 so a bit different).