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ghmm

03/31/15 6:28 PM

#189438 RE: biomaven0 #189437

FGEN:

Thanks for the reference to the correlation between HRCT and FVC.

I was thinking more if they decide to either go head to head or in combination with Esbriet and/or Ofev. A comparison with HRCT may be more favorable then relying on FVC alone where both drugs have shown benefit. I don't know much about nintedanib but I don't believe pirfenidone has ever been shown to have improved fibrosis (aside from anecdotal cases).
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mcbio

03/31/15 9:29 PM

#189446 RE: biomaven0 #189437

Well the Fibrogen IPF data clearly show a correlation between HRCT and FVC

Is FGEN the only one currently targeting CTGF for fibrosis?