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jq1234

03/28/15 6:55 PM

#189302 RE: DewDiligence #189300

It would be tough (but not impossible) to get hypoglycemia benefit on label, <50% chance IMO, the best NVO could hope for is to put data on label without definite claim. Instead, NVO can use degludec's flexible dosing schedule due to its ultra-long half life (24-25 hrs), and combinations with NovoLog, Victoza as major selling point against Lantus. That's NVO's advantage as a fully integrated diabetes specialty pharma.


Here is summary of degludec's benefit during advisory meeting:

http://diatribe.org/issues/49/new-now-next/1