For what it is worth, when I screened for my GILD trial it turned out that I had a extended QT phase (heart arrythmia). I figured it may have been due to a supplement I was taking. I stopped the supplement; the EKG went normal and I treated for 21 weeks w/ Harvoni.
Something like 5 weeks after ending the Harvoni treatment, and while recovering from TX related anemia I ran a 5K race and came in the top 25% of all finishers, while fewer than a half percent of participants were older than me.
EKG just recently checked; still OK. I am *mostly* still alive and well. : )
It's everyone's least favorite drug because of its nasty side effect profile, and yet it still gets widely used, particularly in elderly patients because nothing else works nearly as well for many types of arrhythmias. Regularly kills patients via pulmonary toxicity. That just happened to the elderly mother of a doctor I know.
On a sad note, a leading cardiac surgeon at a Boston hospital recently got shot and killed by a nut who was convinced his mother died because of amiodarone the surgeon had prescribed.
Likely not a significant overlap with the treated HCV population.
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