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F1ash

12/22/14 9:21 PM

#83768 RE: slcimmuno #83765

Nice DD. Thanks.

I thought based on today's posts that visual aids might be a good idea. People are busy and I sometimes forget, though I enjoy them, the longer posts may be too time consuming for others. A picture says 1,000 words very quickly and apparently never lies.

Edit:
I look at it like CTIX is retaking the same test Polymedix already took once. It seems fairly reasonably to expect very similar results. The big deal was the SAE's last time and that has already been answered.
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thefamilyman

12/22/14 10:18 PM

#83776 RE: slcimmuno #83765

Actually the SAEs in Phase 2a were because the patients were being overdosed on Brilacidin. They were giving too much and giving it in a 7 day dosing regimen. The people who designed the Phase 2a trial just did not realize how little of the drug it would take to get the job done.

What we know: B is safer than Dapto (no attributable SAEs -- unlike what ph 2a showed due to poor data followup) and as effective as Dapto across all 3 arms (new info as Big K pointed out). Plus the M-ITT MRSA data is icing on cake. A good CDC resource on MRSA: - slcimmuno