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mr_o

12/03/14 7:26 AM

#184331 RE: mcbio #184320

McBio,

I don't know the particulars of this trial or company so apologies if I'm speaking out of place. On the surface it looks like an economic decision to me. This is an open label ph2 trial, its possible it will save a small cap bio significant funds to run it without a controlled placebo group.
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bladerunner1717

12/03/14 10:22 AM

#184333 RE: mcbio #184320

re: MEIP

Why didn't MEIP run a controlled trial comparing pracinostat+azacitidine to placebo+azacitidine so we could truly gauge how much pracinostat itself is contributing to this data?



In this patient population, it is well-understood how azacitidine performs.

The kind of trial you're asking for in being run by MEIP in MDS.


Bladerunner