"If there are negotiations, CTIX will have a stronger hand by showing they have the funds, or funding ability, in place to go it alone."
There is a burgeoning misconception that an S-3 filing somehow indicates that a company has funds or is able to secure funds and that's simply not true. It's a vehicle that allows for RELATIVELY easy registration of any newly negotiated offerings....note that those negotiations would occur with or without a shelf in place. It can be thought of similarly to the opening of a personal IRA account, which needs to be funded to have any value.
The "ability to go it alone" theory doesn't appear to be supported by the mere existence of an S-3.