Also interesting is the FISH blood test.... I took this test before I had my leukemia treatments to find out what chromosome was defective (broken) Luckily it was my 13q and not my 17q... Anyway....
FISH Test
Fluorescence in situ hybridization (FISH) is a newer that "maps" the genetic material in human cells, including specific genes or portions of genes.
Because a FISH test can detect genetic abnormalities associated with cancer, it's useful for diagnosing some types of the disease. In some cases when the type of cancer has previously been diagnosed, a FISH test also can provide additional information to help predict a patient's outcome and whether he or she is likely to respond to chemotherapy drugs.
In breast cancer patients, for example, a FISH test on breast cancer tissue removed during a biopsy can show whether the cells have extra copies of the HER2 gene. Cells with extra copies of the gene have more HER2 receptors, which receive signals that stimulate the growth of breast cancer cells. So patients with extra copies of the gene are more likely to respond to treatment with Herceptin (trastuzumab), a drug that blocks the ability of HER2 receptors to receive growth signals.
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