Here is an example of the amount of serum needed as treatment for age-related macular degeneration using siRNA.
"Of the 14 patients who each received a single intravitreal dose of Sirna-027, ranging from 100 to 800 micrograms, all of the patients experienced stabilization in visual acuity, and half the patients had improved visual acuity, which appeared to be dose dependent.
"We have the capacity to manufacture 20 to 30 kilos of siRNAs, or other oligos, per year, and can purify more than 80 kilos per year," says Howard Robin, Sirna president and CEO.""
One gram at 800 micrograms per dose will yield about 1250 doses or 1,250,000 per kilogram. So 30 kilos would produce 37,500,000 doses.
At $25 a dose that would provide a sizable revenue stream of close to a BILLION DOLLARS.
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