Replies to post #26264 on Biotech Values

[poorgradstudent]

>are you saying that the mRNA that are silenced would have been reused more often, on average, than the mRNA that are not silenced?<

Think of it as a machine blueprint; if you lose one of two copies of the blueprint, you can still build two of the machines based on the single blueprint.

As it related to RNA / protein: You have two RNA transcripts. Neither is silenced, and you get 2 molecules of protein. Now you silence one of those transcripts. It is still possible to get 2 molecules of protein from the single transcript that is not silenced.

For that reason, the relative change in mRNA level will often appear larger than the change in the protein level.