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genisi

06/14/14 8:07 AM

#179286 RE: DewDiligence #179252

Excluding Abacavir in a Tivicay-based regimen is needed and I was thinking that in the future Tivicay + generic Truvada would be a good single-pill co-formulation. There are more than 20% of patients who cannot start with an NNRTI (due to primary resistance and other reasons), plus Edurant's resistance profile is even weaker than that of Sustiva, so Tivicay + Edurant would not suit also patients with high baseline viral loads. Think the dual nuke + NNRTI or PI or II will maintain the lion share of treatment.