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Re: researcher59 post# 175985

Wednesday, 03/26/2014 2:15:58 PM

Wednesday, March 26, 2014 2:15:58 PM

Post# of 257481

EXEL—…my impression that most cancer drugs are NOT overwhelmingly effective.

What I meant by overwhelming efficacy in #msg-99479851 is not a cure, but rather a very strong hazard ratio (say, 0.4-0.5) on the overall-survival endpoint. The failure to stop the trial at the interim analysis almost certainly rules an HR in that range (or better).

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