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Re: TheProgressive post# 53467

Monday, 02/03/2014 9:48:10 PM

Monday, February 03, 2014 9:48:10 PM

Post# of 405212
since Dapto is brought up, I decide to learn a bit from googling it. Found a wiki page...

http://en.wikipedia.org/wiki/Daptomycin

Even though it was known to have problems with quite a bit of areas, FDA still approves it for Adult use...

The rights to LY 146032 were acquired by Cubist Pharmaceuticals in 1997, which following U.S. Food and Drug Administration (FDA) approval in September 2003 for use in people older than 18 years began marketing the drug under the trade name CUBICIN. Cubicin is marketed in the EU and in several other countries by Novartis following its purchase of Chiron Corporation, previous licensee



In July 2010, the FDA issued a warning that Daptomycin could cause life-threatening eosinophilic pneumonia. The FDA said that it had identified seven confirmed cases of eosinophilic pneumonia between 2004 and 2010 and an additional 36 possible cases. The seven confirmed victims were all older than 60 and symptoms appeared within two weeks of initiation of therapy.



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Nearly 13 years before FDA issued such a warning... I can only imagine how busy they must be. On the other hand, if B is safer alternative, I think FDA would want to fast track it!


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