They constantly had financing problems and were in situations where trials were being delayed do to lack of funds. Many of the write ups talked highly about the successfully completed trials but would uneasily mention that they currently could not fund the next set of trials. They had some borderline unsuccessful trials that also caused issues. B however, was always deemed a huge success.
Still I'd like a better answer because its hard to believe they failed so miserably with a drug with such apparent potential.
What makes me sleep easy at night is CTIX has not had this situation, anytime Leo goes off looking for funds he is able to acquire a favorable financing deal. CTIX also is extremely tight with their burn rate.