(PS) on the cell surface, followed by localized changes in the structure of the cellular membrane and cytoskeleton, blebbing and formation of a microvesicle.22 Interestingly, a genetic defect in the activity of the lipid scramblase leads to the inability of blood platelets to expose PS, or produce procoagulant microparticles, resulting in a rare bleeding disorder known as Scott syndrome.22 There are no published data as to how this, or similar defects in microvesiculation may affect progression, angiogenesis or treatment of solid tumors, but agents that block PS have been already shown to possess anticancer activities,5,23 possibly due to inhibition of microvesicular interactions4 required for angiogenesis and other processes.
There's more, but I hope this contributes to my point...
All the best, John
Disclaimer: Every post, and all my views are only speculative. Do not invest money or any other resources based on these post or opinions. Best of luck and do your own due diligence!