Avid Bioservices Inc (CDMO)

[exwannabe]

I can see the company now setting the wheels in motion for AA.

It would certainly be a legit option to use ORR in Sunrise to garner an AA.

But to do so, they need to make this the predefined primary endpoint. They most certainly can not define the endpoint to be OS, then say "hey look at this ORR data!".

But it really makes no sense for the company to try this path. They would save a year at best, and have a much less clear path.

PPHM has said time and time again that they bare taking the path of following the P2 trial with a P3 OS based trial. This is a reasonable position for PPHM to take. To change the trial design in order to gamble on another endpoint would be dubious.

P.S., I assume you are talking about AA forward going with Sunrise, and not AA on existing data (which is simply absurd).